He is Founder and Member of Scientific Leadership team of TuBerculosis Vaccine Initiative (TBVI). TBVI is a not for profit foundation based in Lelystad, The Netherlands supporting the development new vaccines against human tuberculosis. He is Chair of the Product and Clinical Development team (PDT/CDT) of TBVI, and Chair of Vaccine Program Advisory Group (VPAG) advising DEFRA on a vaccine program against bovine TB in the UK. Jelle Thole is author of over 70 scientific articles on antigen discovery, host-pathogen interactions, and immunology of human and veterinary mycobacterial pathogens including tuberculosis, paratuberculosis and leprosy. He has coordinated large integrated EC FP 6 and 7 projects (TBVAC, NEWTBVAC), aiming to develop new vaccines against tuberculosis.