TBVI’s Mission
To support and facilitate discovery and development of new tuberculosis vaccines that are accessible and affordable for all.
TBVI’s History & strategy
History
TBVI was founded in 2008 to fill the gap in TB vaccine development due to lack of incentives for industry to invest in it. TB is a peculiar disease: it has troubled mankind for thousands of years and even though a childhood vaccine, drugs and diagnostics are available, still today over 10 million people contract the disease yearly and over a million people die of it, more than of any other infectious disease. Improved vaccines, for all target groups, that would protect against lung disease would be a game changer: it would improve health and reduce the economic burden on millions of people as well as the risks of spreading and development of antimicrobial resistance. TBVI has been involved in preclinical and clinical development of a wide range of vaccines and currently several vaccines are in a crucial phase of clinical development.
Strategy
TBVI will continue to support efforts of accelerating clinical development. At the same time, TBVI puts efforts in the design and development of new concepts in the need to diversify the vaccine pipeline as further improvement will be critical to ensure safe, efficacious, and affordable vaccines will be available to achieve the third strategic goal: preventing and stopping TB worldwide. TBVI is involved in each of these 3 goals, but the degree of involvement in each goal is reflected by the colour: the darker, the greater TBVI’s involvement.
TBVI will continue to form strategic partnerships to develop knowledge and tools critically aiding vaccine development.

The TBVI strategic directions are aligned with the Global Roadmap on Research and Development of Tuberculosis Vaccines, developed by the TB vaccine community. TBVI’s focus is on vaccine discovery and development, while ensuring that a new vaccine should be available to, accessible for and accepted by all who need it, aligned with the WHO Global Framework to prepare for Country Introduction of New TB Vaccines for Adults and Adolescents.
TBVI’s projects adding to each of the strategic goals can be found at projects.